The work was planned to evaluate the presence of absence of microalbwninuria, as an early detector
of nephropathy in patients with Familial Mediterranean Fever (FMF). Twenty five patients with FMF and 20
normal healthy controls were included in the study.
Microalbuminuria was detected in 14 (56%) and was absent in 11 (44%) patients with FMF.
Microalbuminuria has no significant relation to age, sex, body weight, body mass index, sample timing and
duration of the disease. The mean value of microalbuminuria in patients under colchicine therapy was
statistically lower than that of patients not receiving colchicine (P < 0.05).
Therefore, early treatment with colchicine in patients with FMF is of great value, moreover regular
follow up by utilizing estimation of rnicroalbuminuria in these patients might be a good prognostic parameter
detecting early nephropathy. |