Posttrartsplantation diabetes mellitus (PTDM) is a major medical problem
that adversely affect the recipient and the graft after renal transplantation.
Its exact incidence has been difficult to determine among previous
studies. This study was done on 1558 patients received live donor renal
allograft. 286 patients (18.2%) developed PT'DM and they constitute the
patient group that was studied against a control group of 316 nondiabetic
recipient. The study showed that the incidence of PTDM was
highest during the first 6 months posttransplantation. The main risk factors
were : older recipient age. positive family history of diabetes mellitus.
obesity. the use of calcineurin inhibitors, the total steroid dose and HCV
infection.. It adversely affect the patient survival and the graft function
and is responsible for many medical complications that affect the recipient. |
