BACKGROUND:Posthemorrhoidectomy pain represents
annoying problem for the surgeon & the patient; despite Its control can be
done by analgesic ladder; it remains in question.
Purposes: The current study investigated the efficacy of topical
tannic acid powder in reducing postoperative pain, promoting wound
healing after open diathermy hemorrhoidectomy and prevention of
secondary hemorrhage.
Patients and methods: A prospective, randomized trial was
conducted to ninety-seven patients suffering from grade 3 or 4 internal or
external hemorrhoidal disease; to compare posthemorrhoidectomy pain &
wound healing with the use of topical tannic acid applied to the surgical
site. vs. placebo carrier. Postoperative follow up was for 3 months.
Results:Topical tannic acid patients improved postoperative pain
at lg 2 days (VAS: 1.2 ± 0.4 vs. 8.2 ± 0.6; P <0.05) and 7th day (VAS:,
3.6 ± 0.6 vs. 6.3 ± 0.5; P <0.05) & improved wound healing significantly
(Postoperative edema: (mean score, 3.0 vs. 7.0; P <0.05) & Overall
wound healing: (mean score, 4.0 vs. 6.0; P <0.05)) despite there was no
difference as regard Primary vs. secondary healing (P >0.05). Also
secondary hemorrhage in the topical tannic acid group was significantly
less (mean score, 2.0 vs12.0; P <0.05). |