Publications of Faculty of Medicine:ESTIMATION OF SERUM TRANSAMINASE LEVELS IN CHILDREN WITH SUSPECTED BLUNT HEPATIC INJURY: Abstract

Title:
ESTIMATION OF SERUM TRANSAMINASE LEVELS IN CHILDREN WITH SUSPECTED BLUNT HEPATIC INJURY
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Abstract:

A prospective study of 47 consecutive children with suspected blunt abdominal trauma was undertaken. Hepatic injuries were documented in 12 patients by laparotomy and / or abdominal computed tomographic (CT) scan. Children with hepatic injuries had statistically significant elevations in serum transaminase levels (Asparlate aminotransferase (AST or SGOT) and alanine aminotransfera.se (ALT or SGPT) on admission. More over all children with liver injuries had admission AST more than 280 IU/L and ALT mor thatn 140 IU/L. Only those children with such high levels of AST and ALT are at significant risk for hepatic injury . We recommend the consideration of high AST and ALT levels in a haemodynamically stable child with blunt abdominal injury as an indication for obtaining CT scan whenever feasible even when the clinical evaluation is relatively reassuring.