Abstract
Testicular ischaemia has been implicated in the etiology of
testicular pathology that causes male infertility. This study was designed
to investigate the ultrastructural changes in both testes of the rat after
bilateral ligation of testicular vessels and the changes in the contralateral
testis after unilateral ligation.
Thirty adult male albino rats were used in this study and were
equally divided into three groups; Sham operated animals (control
group), animals with bilaterally ligated testicular vessels and animals
with unilaterally ligated testicular vessels. The animals were left for 6o
days after ligation and the testes were then collected from each animal
and were prepared for both light and electron microscopic study.
Bilateral ligation of testicular vessels led to degenerative changes
in the seminiferous tubules and the latter contained degenerated
spermatognia and many inflammatory cells. The interstitium of the testis
contained normal Leydig cells surrounded with dense connective tissue
fibres.
On the other hand, unilateral ligation of testicular vessels had no
effects on the contralateral testis.
In conclusion, these results showed that bilateral ligation of
testicular vessels caused massive necrotic changes in both testes, while
unilateral ligation gave no contralateral testicular changes. |
