Publications of Faculty of Medicine:SPERMATIC GRANULOMA OF THE RAT VAS DEFERENS FOLLOWING VASECTOMY LIGHT AND ELECTRON MICROSCOPIC STUDY: Abstract

Title:
SPERMATIC GRANULOMA OF THE RAT VAS DEFERENS FOLLOWING VASECTOMY LIGHT AND ELECTRON MICROSCOPIC STUDY
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Abstract:

Abstract Spermatic granuloma of the vas is considered as one of the complications following vasectomy. In the present work light and electron microscopic study of such granuloma was performed so as to determine whether it exhibts the morphological criteria of granulomata described in other systems or not. This study can also be considered as a preliminary step to determine the efficacy of vasectomy as one of the methods used for family planning. Vasectomy was done using the technique of division and ligation in sixteen adult albino rats . Half of them were sacrificed after two months and the rest were sacriffced after five months. Granulomata formed were extractd and prepared for both light and electron microscopic study. The granulomata are formed of cellualr wall of variable thickness surrounding a central spermatic mass . Different types of cells simulating those described in other granulomata were found e.g. macrophages & plasma cells and lymphocytes. Numerous giant cells as well as multivesicular bodies were also detected in the later satges after vasectomy