Abstract
Spermatic granuloma of the vas is considered as one of the complications
following vasectomy. In the present work light and electron microscopic
study of such granuloma was performed so as to determine whether
it exhibts the morphological criteria of granulomata described in other
systems or not. This study can also be considered as a preliminary step
to determine the efficacy of vasectomy as one of the methods used for
family planning. Vasectomy was done using the technique of division and
ligation in sixteen adult albino rats . Half of them were sacrificed after
two months and the rest were sacriffced after five months. Granulomata
formed were extractd and prepared for both light and electron microscopic
study.
The granulomata are formed of cellualr wall of variable thickness surrounding
a central spermatic mass . Different types of cells simulating
those described in other granulomata were found e.g. macrophages &
plasma cells and lymphocytes. Numerous giant cells as well as multivesicular
bodies were also detected in the later satges after vasectomy |