Abstract
The relationship between the testis and the parotid gland has been
poorly investigated. This study deals with the structure of the parotid
gland and its changes after orchiectomy . antiartdrogen (flutamide) and
testosterone substitution. The rat parotid glands of control and experimental
animals (orchirmectomized . orchiectomized with testosterone substitution
and antiandrogen) were analyzed by light and electron microscopy
. Orchiectomy and antiandrogen have more or less similar effects on
the parotid gland. Both reduced secretory activity of the gland which was
manffested by decreasing the secretory granules. vacuolations of the cytoplasm
and degeneration of mitochondria . Exogenously given testosterone
can prevent the mentioned effects of orchiectomy on the parotid
gland. It is concluded that orchiectomy and antiandrogens affect the rat
parotid gland demonstrating the existence of an interaction between the
testis and parotid gland |
