For identification of serologic markers of HBV in schistosomal children and its reflection
on liver function status, this study included 80 children aged 6-15 years; 60 children
having active schistosomiasis and 20 non schistosomal ones as control. Hepatitis B
markers were found in 63.3% and 35 % of schistosomal and non schistosomal children
respectively. The serologic BEV markers were 11BsAg (183%), HBsAb (33.3%),
1113cAb (33.3%), HBeAb (83%), HBsAg + HBsAb (1.7%) and 11BeAb + HBcAb in
1.7% of schistosomal children . The mean values of scum bilirubin, globulin, transiuninases
(AT!', AsT) and alkaline phosphatase were significantly increased in schistosomal
children with positive HBV markers than schistosomal ones with negative markers and
than non schistosomal children (with positive or negative markers), while the mean values
of total serum protein and serum ablumin were significantly more lowered in schistosomal
children with positive HBV markers than schistosomal ones with negative markers
and than non schistosomal children (with positive and negative markers). Since our results
revealed that dual infection with schistosomiasis and HBV may lead to severe liver
impairement, so population living on schistosomiasis endemic area might benefit if effectively
immunized against hepatitis B virus infection. |
