| Title: | STUDY OF SERUM TUMOR NECROSIS FACTOR a AND INTERLEUKIN
6- IN PATIENTS WITH RHEUMATOID ARTHRITIS AND THEIR
RELATION WITH CLINICAL AND LABORATORY VARIABLES |
| Full paper | Not Available |
| Abstract: |
Serum levels of TNFct and IL.6 was studied in fifteen rheumatoid arthritis patients, their ages ranged between 30-63 years with a mean age of 48±9.6 . Another eleven healthy subjects were chosen as control group . The aim of the study was to Correlate TNFa and IL-6 with clinical indicators of disease activity . There was significant increase in serum level of TNFcc and IL-6 in rheumatoid arthritis patients as compared to control group. Also in patients with rheumatoid arthritis serum levels of TNFa and 1L-6 correlated positively with clinical variables of disease activiety . We concluded that the measurement of TNFa and IL-6 in serum seemed to provide a good index as acute phase reactant and also yield more direct reflection of Joints inflammation and destruction compared with markers of inflammation |