Publications of Faculty of Medicine:ANTICYCLIC CITRULLINATED PEPTTDE ANTIBODIES: ROLE IN THE DIAGNOSIS OF RHEUMATOID ARTHRITIS AND DIFFERENTIATION FROM PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION WITH ARTICULAR MANIFESTATIONS.: Abstract

Title:
ANTICYCLIC CITRULLINATED PEPTTDE ANTIBODIES: ROLE IN THE DIAGNOSIS OF RHEUMATOID ARTHRITIS AND DIFFERENTIATION FROM PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION WITH ARTICULAR MANIFESTATIONS.
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Abstract:

Objecti^e: The study is undertaken to assess the value of anticyclic citrullinated peptide antibodies (anti-CCP Abs) as specific serological marker for the diagnosis of RA and its relation to disease activity. It is also meant to explore if this marker can be used to distinguish between RA patients and hepatitis C virus (HCV) infected patients with articular manifestations. Methodology: After full history taking and thorough clinical examination, serum samples from 27 RA patients, 39 HCV infected patients and 25 healthy subjects, were tested for IgG RF and anti-CCP antibodies by latex agglutination and commercial second generation anti-CCP enzyme-linked immunosorbant assay (ELISA) respectively.