Publications of Faculty of Medicine:STUDY OF PHYSICAL GROWTH; SKELETAL MATURATION AND SERUM OSTEOCALCIN LEVEL IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS AND CONTROL: Abstract

Title:
STUDY OF PHYSICAL GROWTH; SKELETAL MATURATION AND SERUM OSTEOCALCIN LEVEL IN PATIENTS WITH JUVENILE RHEUMATOID ARTHRITIS AND CONTROL
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Abstract:

Physical growth, skeletal maturation and serum osteocalcin level were studied in 84 patients with juvenile rheumatoid arthritis (28 males and 56 females) ranged in age between 3 years to eighteen and half years with mean age 1.1.60 years and on 84 healthy controlled matched as re gard to age, sex and socineconomic status with the patients. The results showed significant growth retardation (in weight and height), delayed skeletal maturation (TW220-bones and carpal bone age) and serum osteo calcin level in all patients witlijuvenile rheumatoid arthritis (JRA). All the parameters of the male and female patients were less than that of the control and the females were more affected than males. As regard to the duration of the disease a higher percentage of the parameters were below the 5th or 3rd centile in patients with disease duration > 3 years than that in patients with disease duration < 3years. Also in patients with sys temic onset, both weight and height were below the 511i centile in 73.33% and RUS, TW220-bones and carpal bones age were below the 3rd centile in 23,33%, 60% and 50% respectively. These percentages were heigher than that in pavdarticular and pdlyarticular onset Also, it was observed that, in patients receiving corticosteroid, weight and height were below the 5th centile in 75% and 83.3% respectively and RVS, TW^O-bones and carpal bones were below the 3rd centile in 27.78%, 72.22% and 75% respectively