Lipid peroxides, superoxide dismutase (SOD), glutathione peroxidase(GPX) and
selenium were studied in 30 patients suffering from rheumatoid arthritis (RA). The
study also included 15 apparently healthy individuals served as a control group.
Lipid peroxides was significantly increased in RA patients as compared to the
control group, meanwhile, SOD, GPX and Selenium were significantly decreased in
RA patients as compared to the control group.
As regards RA disease activity, we found that the level of selenium was significantly
decreased in more active patients, so it can be considered as a marker of disease
activity, while there were no significant differences in the levels of SOD, GPX and
lipid peroxide as regards disease activity.
By correlation coefficient, no significant differences were found between all the
parameters in RA patients. |
