Publications of Faculty of Medicine:Role of diffusion-weighted MR imaging^*. in discrimination between the intracranial cystic masses : Abstract

Title:
Role of diffusion-weighted MR imaging^*. in discrimination between the intracranial cystic masses
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Abstract:

Objective: Discriminating pyogenic brain abscesses from cystic or necrotic tumors is sometimes difficult with CT or conventional MR imaging- Diffusion MR imaging is a valuable diagnostic test in cases of intracranial cystic masses. Methods: This work was conducted from July 2008 to June 2013 on 90 patients; 43 males and 47 females. Their ages range from 5 to 70 years. All patients were subjected to routine MRI examina tion and diffusion weighted imaging using 1.5 T MRI scanner. Gadolinium was given to some cases on routine MRI. Diffusion weighted imaging was performed with a single-shot spin-echo echoplanar pulse sequence (b = 0-1000 s/mm2). The apparent diffusion coefficient values and ratio were measured. Results and conclusions: Patients in this study were categorized into three main groups; first group is brain abscesses (36 cases), 91.6% of them showed restricted diffusion, second group is malignant cystic or necrotic brain tumors, 28 cases of high grade necrotic glioma, 60.7% of them are free diffusion, and third group is benign cystic masses, arachnoid and epidermiod cysts (11 cases); all arachnoid cysts are free diffusion. From these results diffusion-weighted imaging is playing an important role in discrimination of cystic intracranial masses. © 2014 Production and hosting by Elsevier B.V. on behalf of Egyptian Society of Radiology and Nuclear Medicine. Open access under CC BY-NC-ND license