Pituitary testicular hormonal axis was studied in fifteen (15) male patients
with chronic renal failure treated with regular hemodialysis, their ages ranged
from 27-55 years, and in other ten (10) male renal transplant recipients (CRF
patients whose treated by successful renal transplantation), they were studied 9-18
months after renal transplantation, their ages ranged from 27-37 years. Ten (10)
healthy adult males were chosen as control group, their ages ranged from
27-48 years. Assessment of follicle stimulating hormone (FSH), luteinizing
hormone (LH), prolactin, testosterone and dehydroepiandrosterone sulfate in
serum was done, also testosterone suppression test to luteinizing hormone was
also done in a random group of dialyzed patients . (7 patients) and we found serum
FSH,LH and _prolartin were significantly increased (P <0.001) in dialyzed group
as compared to co; 'trot group while testosterone and dehydroepiandrosterone
sulfate were significantly decreased (P <0.001), the testosterone suppression test
m dialyzed group showed integrity of this axisin renal transplcini group, serum
PSI!, prolactin, testosterone and dehydroepiandrosterone sulfate were non
significantly changed when. compared to control group but LH was significantly
decreased (P <0.001) when compared to both control and dialyzed groups.
From this study, we conclude that pituitary testicular hormonal axis still
intact in those patients with CRP undergoing regular hemodialysis and that renal
transplantation can correct the pituitary testicular hormonal pattern more or less
near to normal |
