This work was performed to study the serum calcium and phosphorus in patients
with obstructive airway diseases. This study included 50 asthmatic patients (reversible
airway obstruction) and 50 patients with COPD (irreversible airway obstruction), in
addition to 20 normal healthy mon smoker subjects as a control group the only obvious
change was the hypocalcemia in both the asthmatic group and COPD group but the
underlying cause may be different. This hypocalcemia was not due to or causing any
change in the serum phosphorus concentration, also not due to the steroid therapy which
may be used in the management of these diseases. The resultant hypocalcemia was not
affected either by type of asthma (in asthmatic group) or by the degree of airway
• obstruction expressed as FVC, FEY,, FEV,/ FVC% and FEF25.75 % . An assay of hormones
that control calcium and phosphorus homeostasis together with correlation with the
changes in acid-base and blood gases parameters that observed in these patient is
recommended. |