Publications of Faculty of Medicine:STUDY OF ERYTHROCYTE MEMBRANE LIPID PEROXIDATION DURING MYOCARDIAL INFARCTION: Abstract

Title:
STUDY OF ERYTHROCYTE MEMBRANE LIPID PEROXIDATION DURING MYOCARDIAL INFARCTION
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Abstract:

Fasting blood was taken from 15 patients with myocardial infarction and 15 healthy controls. Membrane lipid peroxidation in erythrocytes of both groups was examined and compared to demonstrate its possible relationship with myocardial infarction. Lipid peroxidation was assessed in fresh erythrocytes by quantitating malondialdehyde level. Malondialdehyde concentration was significantly higher (PC 0.05) in patients with myocardial infarction during the initial 48 hours after an attack. Twelve days after an attack, malondialdehyde decreased but still its level was higher than controls. It was concluded that lipid peroxidation is involved in cardiac disease specially myocardial infarction and accompained by an increase in the production of malondialdehyde