Background: Although hepatic resection is one of the most effective
treatments for hepatocellular carcinoma (HCC), the long term results of
hepatic resection of this malignancy are far from satisfactory. The potential
benefits of hepatectomy for patients with HCC have not been fully delineated.
This study aimed to identify surgical outcomes of 18 consecutive
cirrhotic patients with I-ICC undergoing hepatic resection.
Study Design: 18 patients with cirrhotic liver underwent hepatic resection
between March 2002 and January 2007. We had 14 men and 4
women. The mean age was 55 years with a range between 42 and 67
years.
Results: The 30-day (operative) mortality rate was one case (5.5%)
and there was one additional late death (5.5%). Ten patients (62.5%) had
recurrence after curative resection. Major hepatectomy was performed in
14 patients (77%) and the other 4 (22%) had minor hepatectomy In our
study, the overall survival of patients after 3 years was 43.75 % while
the disease-free survival was 37.5%.
Conclusion: The survival rate after operation remains unsatisfactory
mainly because of the high recurrence rate. The improved care of cirrhotic
patients, early detection and effective treatment of recurrent HCC may
play an important role in achieving better prognosis and survival after operation. |