Twenty seven patients having bilateral active vernal keratocordunctivitis
(VKC): 5 mild (all palpebral), 14 moderate (9 palpebral and 5
mixed) and 5 severe (all mixed) were treated with a new non-steroidal
anti-inflammatory eye drops (Diclofenac Sodium 0.1%) for 4 weeks. Two
patients did not complete treatment
All symptoms disappeared in mild cases except itching in one patient.
Total score of foreign-body sensation was markedly reduced in moderate
and severe cases (92% and 75% respectively), while total score of photophobia
showed the least decrease in both groups (63.6% and 58.33% respectively).
Conjunctival hyperaemia and discharge disappeared in all mild cases
with treatment. The greatest decrease in total score of clinical signs was
in conjunctival hyperaemia for moderate cases (90.9%) and in conjunctival
• discharge for severe cases(7096). While the least decrease was in superficial
punctate keratitis (SPK) (46.6% and 33.33% in moderate and severe
▪ cases respectively). In all cocPs tarsal papillae did not disappear but became
less hyperaemic and slightly smaller in size.
Diclofenac Sodium eye drops 0.1% could be considered an additional
tool in treatment of VKC as it showed efficacy in managing most of symptoms
and signs. Its action is similar to systemic non-steroidal antiinflammatory
drugs (NSAIDS) without having their side effects. |
