Twenty seven patients having bilateral active vernal kerato -
conjunctivitis (VKC): 8 mild (all palpebral), 14 moderate (9
palpebral and 5 mixed) and 5 severe (all mixed) were treated with a
new non-steroidal anti-inflammatory eye drops (Diclofenac Sodium
0.1%) for 4 weeks. Two patients did not complete treatment.
All symptoms disappeared in mild cases except itching in one
patient. Total score of foreign-body sensation was markedly reduced
in moderate and severe cases (92% and 75% respectively),while total
score of photophobia showed the least decrease in both groups
(63.6% and 58.33% respectively).
Conjunctival hyperaemia and discharge disappeared in all mild
cases with treatment. The greatest decrease in total score of
clinical signs was in conjunctival hyperaemia for moderate cases
(90.9%) and in conjunctival discharge for severe cases(70%). While
the least decrease was in superficial punctate keratitis (SPK)
(46.6% and 33.33% in moderate and severe cases respectively). In
all cases tarsal papillae did not disappear but became less
hyperaemic and slightly smaller in size.
Diclofenac Sodium eye drops 0.1% could be considered an
additional tool in treatment of VKC as it showed efficacy in
managing most of symptoms and signs. Its action is similar to
systemic non-steroidal anti-inflammatory drugs (NSAIDS) without
having their side effects. |
