To investigate the effects of lead acetate on the spiral ganglion, an experiment
was performed on 20 guinea pigs 10 animals were considered
as control group, and 10 animals were injected intraperitoneal with 1%
lead orPtate solution once a week for 5 constitutive weeks (20 mg/kg/
week) The light microscope showed degeneration of wallerian type of
nerve fibers of spiral ganglia. The electron microscope findings were as
the following: nerve-fibers with disruption and disorganisation of myelin
sheeth with normal axoplasm were observed other fibers showed complete
abscence of myelin sheeth with vacuolization of axoplasm. |
