A total of 72 bilharzial mansonian school children aged 6-12 years were
studied before and six months after praziquantel (PZQ) treatment. After
treatment, 21 cases showed reinfection while 51 were resistant. Using ELISA
specific antibody assays titre levels of IgM, IgG, IgA At IgE for soluble egg
antigen (SEA) and soluble worm antigen (SWAP), were higher among
resistant cases than among reinfected ones before and after treatment. The
levels of specific IgA & IgE among resistant cases were significantly higher
than among reinfected rases after treatment. This may indicate the integiity of
immune system and prominant Immoral immune response. |
