lucks a precise definition and is of unknown elioloay.
This condition usually involves the palms, soles
and axillae, where the eccrine sweat glands are con
centrated and show an exaggerated response to men
ial stimuli"^.
Many treatments for hyperhidrosis have been de
scribed, but few are effective and acceptable, and
non has been without potential complications. Topi
cal agents such as aluminum chloride may cause irri
tation. Iontophoresis may provide relief", especially
for palmar and solar hyperhidrosis. but is less effec
tive for axillary sweating. It is also time consuming
and requires numerous treatments and maintenance
therapy. Systemic amicholinergic agents frequently
have unacceptable side effects^2*. Upper thoracic
sympatheciomy often fails to cure axillary and pal
mar hperhidrosis, and complications may include
pneumothorax, pneumonia, Homer's syndrome and
compensatory hyperhidrosis in noninnervated areas.
Surgical excision of axillary sweat glands may be
associatedwith scar contractures*^*.
Botulinum toxin is a new and effective treatment
for hyperhidrosis of the axillae, palms, soles and
gustatory sweating. Chemodenervation with botuli
num toxins appears to offer a safe alternative to sur
gical interventions, ongoing topical applications, or
frequent treatment modalities for reducing sweating,
with no significant complications or side effects*4*. |
