Background: T cell activation is
thought to play an important role
in the pathogenesis of psoriasis.
Activity of serum adenosine
deaminase (ADA), amainenzyme
in purinemetabolismis a nonspecificmarker of
T cell activation.
Objective: To determine the level of
adenosine deaminase activity in serum
of psoriatic patients and to investigate its
associationwith disease activity.
Subjects and Methods: The study was
conducted on 30 patientswith psoriasis and 30
apparently healthy controls. The patients were
scored with PASI (psoriasis area and severity
index) and divided into two groups: Group I, |