Publications of Faculty of Medicine:Serum Adenosine Deaminase Activity as a Serological Marker in Psoriasis: Abstract

Title:
Serum Adenosine Deaminase Activity as a Serological Marker in Psoriasis
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Abstract:

Background: T cell activation is thought to play an important role in the pathogenesis of psoriasis. Activity of serum adenosine deaminase (ADA), amainenzyme in purinemetabolismis a nonspecificmarker of T cell activation. Objective: To determine the level of adenosine deaminase activity in serum of psoriatic patients and to investigate its associationwith disease activity. Subjects and Methods: The study was conducted on 30 patientswith psoriasis and 30 apparently healthy controls. The patients were scored with PASI (psoriasis area and severity index) and divided into two groups: Group I,