Non-steroidal anti-inflammatory drugs have a predominantly peripher al site of action by blocking the local synthesis qfprostaglandins. The aim
of this study was to compare and evaluate whether the additional of
small dose ketoprofen and ketorolac to lidocaine during intravenous re
gional anaesthesia (IVRA) would improve the quality of postoperative analgesia. Sixty patients undergoing upper limb IVRA for minor sugery
were randomly assigned to three double-blind groups, group 'A' (placebo),
group 'B' where 15 mg ketoprofen was mixed with lidocaine 0,5% for
IVRA administered Lv. after tourniquet inflation and group C where 5 mg
ketorolac was added to the local anesthetic for IVRA Mean doseoffen
tanyl consumption inira operatwely was significantly lower (P < 0,05) in
groups B and C when compared with group A durationl of post operative,
analgesic was significantly longer (P 0<005) in group B (14^11)... and, group C (1510) when compared with group A ( 1.40.7), but not signifi
cant (P< 0.50) between group Band C. ••.....; V
Analgesic requirements remained significantly lower in groups B and .
C when compared with group A but not significant between groups B & C
Pain scores were significantly lower in groups B and C when compared
with group A. but was not significant between groups B and C.We cqncit- •
laded that 15 mg ketoprofen and 5 mg ketorolac added to lidocaine 0.5%. during IVRA improves the quality of intraoperative and postoperative
analgesia and ketoprofen was as efficacious as ketorolac.; |
