This work aimed to study the immunoglobulin levels of the saliva in patients
with upper aero-digestve tract (LIAM7 carcinomas as an indicator of
I n1 humoral immunity. Saliva was collected and by the use of Carlson
cups the colostral IgA monomeric IgG and IgM were determined in the
saliva of 34 pariPnts with UADT carcinomas. 19 patients with genitourinary
carcinomas and 58 controls.
There was statistically significant reduction in salivary IgA and rise of
IgM in patients with UADT carcinomas as compared with the control group
and patients with genito-urinary carcinomas.
This denotes that the local immune mechanisms are disturbed in UADT
carcinomas. This disturbance may have a role in the pathogenesis of
these diseases and may be used as an early indicator for them. |