This study was designed as a trial. to evaluate the combined use of both hypotensive anesthesia and autotransfusion strategies for reduction of allogeneic blood transfusion during surgical correction of scoliosis. Twenty (ASA I-11) patients were randomly allocated in two equal groups, group I received normotensive anesthesia and group II received hypotensive anesthesia and underwent intraoperative autotransfusion using cell saver (Haemacell System 350), both groups were assigned to receive allogeneic banked blood if they required. During surgery patients were monitored for heart rate (1-112), mean arterial pressure (MAP), core temperature, central venous pressure (CVP) and urine output. Intraoperative blood loss (10BL), postoperative blood loss (POBL) and total blood loss (TBL) were defined and calculated as a percentage of estimated blood volume (EBV) and amount of blood transfusion required was recorded, transfusion trigger hemoglobin concentration was considered to be <7 gm/ dl. There was a significant decrease of10BL, POBL, and TBL in group II compared to group L All patients included in group I and 8 patients in group II required allogeneic blood transfusion. Moreover, there was a significant (P<0.05) decrease of the total number of blood units consumed in group if. There was a positive significant correlation (r=0.696. P=0.025) between the duration of surgery and the IOBL in group I, and between MAP and total number of blood units used (r=0.716, P=0.02) and both 10BL, (r=0.716, P=0.02) and TBL (r=0.845, P=0.002) in group IL |
