The study comprised 30 (LISA grades II &.III) patients aged 47-72 years, randomly allocated into three equal groups (n=10) according to type of anesthesia administered and number of lungs ventilated: Group I anesthetized using continuous intravenous general anesthesia (GA) with two-lung ventilation (TLV), group II received GA with one-lung ventilation (0)1) and group III received thoracic epidural anesthesia (TEA) combined with GA with OLV. Arterial and venous blood gases, heart rate (11R), and mean arterial pressure (MAP) were measured during TLV, 15 (OLV+15) and 30 min after beginning OLV (OLV-1-30). Duration of surgery, the number of blood bags used for transfusion, and postoperative analgesia requirements were recorded. Hemodynamic parameters showed nonsignificant changes between patients administered GA, whereas there was significant (P<0.05) decrease in MAP and HR in TEA group and 7 patients required administration of 10 mg of IV ephedrine in group 1ff. OLV resulted in significant (P<0.05) reduction of Pa02, Sa02, Ca02 and Cc02 in groups ll and III at OLV+15 compared to group I. and in group III compared to group H. At OLV-'-30, there was significant (P<0.05) reduction of all measured parameters in groups Hand III compared to group I, and in group III compared versus group IL AU patients showed an increased Qs/ Qt% 15 and 30 min after OLV, however, the increase was significant (P<0.05) in groups H and III compared both to group land to their percentages measured during TLV. Despite the non-significant difference between groups II and III |
