Until a few years ago, the testis was considered to be unresponsive
to thyroid hormones. Recently T3 receptors located in the nuclei of
Sertoli and Leydig cells of the rat testis have been shown to increase
during the fetal and perinatal periods, and tend to decrease until puberty.
In this study, we investigated the histological, histochemical and
steroidogenic of the testis in euthyroid, hypothyroid and hyperthyroid
adult rats, to detect whether the deficiency of 13 receptors in adult
testicular tissue prevents the thyroid hormone effects on the testis or not.
30 adult's male albino rats were used in this study. Many histological and
histochemical changes were observed. Also, testicular weights were
significantly increased in hyperthyroid and decreased in hypothyroid rats.
These results indicate that thyroid hormones still can regulate the
testicular functions in spite of deficiency of 13 receptors in the testis of
adult rats. |
