This study was designed to evaluate the local co-administration of magnesium sutfate through the spinal route during bupivaeaine spinal anesthesia and comprised 60 patients assigned to undergo variant anal surgeries under spinal anesthesia using bupivaeaine 0.5% in a dose of 3 ml (Control group) or in a dose of 1.5 ml mixed with 50 mg MgSO4 (Study group). The efficacy of postoperative analgesia was documented every 20 minfor 3 postoperative hours, using visual analogue scale (VAS), the type of analgesia needed and number of requests were also defined. The de gree of sedation was assessed 30 & 120 minutes after admission to the recovery room using the Brussels Sedation Scale. The quality of postoper ative pain relief despite being excellent in both groups was statistically superior in study group. There was a significant (P<0.05) decrease in tiwnber of patients required analgesia in study group with a significantly (psO.05) longer duration of postoperative analgesia. Moreover, there was d significant (P<0.05) decrease in the mean number of requested fentanyl iqjectipns. in study group. Sedation score showed a nonsignificant (9^0.05) decrease in study group at 30 and 120 minutes after end of sur gery compared to control group. There was a significant (P<0.05) de crease of blood pressure estimates determined throughout the follow-up period in both groups compared to their baseline estimates with a non significant (P>0.05) decrease of blood pressure measures in study group compared to control group during follow-up. Thus, we can conclude that tjip use of magnesium sulfate via spinal route is safe and could help to re^ ditce the dose of local anesthetic used and postoperative opioid require ment |
