Serum total sialic acid, serum cholesterol and plasma
fibrinogen were assayed in fifteen patients (10 males and 5 females)
who had a myocardial infarction. Their ages ranged 45- 58, with a
mean age of 52 ± 3.5 years. Another fifteen normal individuals (9
males and 6 females) were used as a control group. Their ages
ranged 41 - 57 , with a mean value of 47 ± 4.5 years. The mean
serum sialic acid in acute myocardial infarction group was
significantly higher (P <0.001) when compared with the control
group. There was no sex difference with respect to serum sialic
acid and , also its level did not correlate with the age of subjects. A
significant positive correlation between serum sialic acid and plasma
fibrinogen (r — 0.624, P <0.01) and also with serum cholesterol (r
0.499, P < 0.05) in acute myocardial infarction group was found.
Also there was a significant positive correlation between serum
sialic acid and plasma fibrinogen in control group ( r = 0.98, P <
0.001). It was therefore , concluded that the measurement of sialic
acid in serum seemed to provide a rapid and simple index as acute
phase reactant in myocardial infarction patients. |
