| Title: | PAIN PREVENTION DURING INJECTION OF PROPOFOL. A COMPARISON BETWEEN LIGNOCAINE PRETREATMENT, METOCLOPRAMIDE PRETREATMENT AND LIGNOCAINE MIXED WITH PROPOFOL |
| Full paper | Not Available |
| Abstract: |
In this prospective, randomized., double-blind study, we studied the incidence and severity of painful injection of propofoL One hundred AIM I, II patients scheduled for elective surgery under general anesthesia were recruited into this study. The patients were randomized into four groups each 25 patients. Group A (placebo) receives 2ml saline before propofol, group B receives 2mL lignocaine 2% before propofol, group C receives propofol mixed with 2mL lignocaine 2% and group D receives 10mg metoclopramide before propofoL The incidence of pain was less in patients pretreated with lignocaine (group B) 32% (p<0.01), patients of lignocaine mixed with propofol (group C) 28% (p<0.01) and patients given metoclopramide before propofol (group D) 28% (p<0.01) than in patients receiving placebo (group A) 88%. The mean pain score was less in patients in group B (0.6) or group C and (0.4) than group A (1.7). A large difference 60%84% of pain score was found between group B compared with group C and D with less pain in group C. D than group B. there was no statistical significant difference as regards the percent of patients in pain and quality of pain between group C and D. We conclude that pretreatment with lignocaine 40mg before propofol improves painful injection but less than pretreatment with lOrng metoclopramide or lignocaine 40mg mixed with propofoL |