Publications of Faculty of Medicine:COMPARATIVE EVALUATION OF ALFENTANIL WITH PROPOFOL OR SEVOFLURANE FOR END OTRACHEAL INTUBATION IN PEDIATRIC WITHOUT MUSCLE RELAXANT : Abstract

Title:
COMPARATIVE EVALUATION OF ALFENTANIL WITH PROPOFOL OR SEVOFLURANE FOR END OTRACHEAL INTUBATION IN PEDIATRIC WITHOUT MUSCLE RELAXANT
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Abstract:

Intubation without muscle relaxant may be needed especially in pediatric short procedure. Although suxamethonium produces rapid profound neuromuscular block. it have many potential problems. Non-depolarizing neuromuscular blocking agents are an alternative but, slower in onset and have a longer duration of action. Propofol and sevoflurane may provide adequate conditions for intubation without neuromuscular blocking agents in pediatric. We studied 60 ASA I or H children undergoing elective surgery. Patients allocated randomly to one of two groups. Group P (GP) received lignocairte lmg kg-1 followed by alfentanil 15 mg kg-1 2 min before propofol 2.5 mg kg-1 was given. In group S (GS) patients received lignocaine I mg kgt1 followed by alfentartil 15 pg kg-1 and induction of anesthesia was done by sevoflurarte start by 3% concentration, which increase gradually until end tidal concentration was 3%, Laryngoscopy and intubation was performed, in GP 1min after propofol and in GS 3min after stabilization of end tidal sevoflurane to 3%. Intubation conditions were assessed and recordecL Duration of induction and intubation were estimated. Complications during induction. intubation. and after extubation were recorded.