dely replaced the traditional open cholecystectomy. However, highpressure pnewnoperitoneum was accused for precipitating some intraoperattve hemodynamic effects and postoperative shoulder-tip pain (STP). The objectives of this study were to determine the influence of lowpressure pnewnoperitoneum on the frequency and intensity of shouldertip pain and body hemodynamics in patients undergoing taparoscopio cholecystectomy. The study comprised 70 chronic calcular cholecystitis patients (25 men & 45 women]. Thirty-three patients (Group D were as signed to undergo IX under high-pressure (13-15 mrhHg) and 37 patients under low-pressure (7-9 mmHg) fGroup ID. Intraoperative monitoring in cluded measurement of heart rate (HR), systolic, diastolic blood pres sure, and mean arterial blood pressure (MAP) was calculated. The fre quency of postoperative SIP was determined and its intensity was determined using utsual analogue scale charts (VAST. There was a signifi cant (P<0.05) increase in MAP in both groups at 5 min. after insufflation arid after tilting the patient to reversed Trendelenberg position (RIP), but there was a signi/icant decrease of MAP in Group II as compared to Group I CX?^7.716, P<0.05). There was a significant reduction ofbothfrequency (13.5% vs. 33.3%) and intensity ofSTP in low-pressure group com pared to high-pressure group. This difference was especially significant 6,12,24 hours postoperatiuely. Moreover there was a positive significant correlation between the insufflated pressure and the frequency (r=0.691 |