Publications of Faculty of Medicine:REVERSAL AND POSTOPERATIVE RESIDUAL CURARIZATION WITH DIFFERENT NEUROMUSCULAR BLOCKING DRUGS : Abstract

Title:
REVERSAL AND POSTOPERATIVE RESIDUAL CURARIZATION WITH DIFFERENT NEUROMUSCULAR BLOCKING DRUGS
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Abstract:

Post-operative resirli ml curarization (PORC) is a common cause of post operative morbidity and mortality. This study was performed on 60 adult patients aged 18- 50 yrs, weighing 40-80 kg of ASA 1 & 11 scheduled to undergo elective moderate operations requiring muscle relaxants . Patients were randomly divided into three equal groups according to the neuromuscular blockers used namely; atracwium, pancuroniurn, and pipecuronium group (20 patients in each). Neuromuscular monitor; relcvcograph; was used in all patients. There were signcantly shorter recovery times ( reversal time , time to sustain head lift for 5 seconds and time to good hand grip) in atracurium group than those in pancuronium and pipecuronium groups. However, there was no significant difference between pancuroniurn and pipecuronium group as regard recovery times. Moreover, there was no significant difference between intermediate and long acting neuromuscular blockers as regard the incidence of PORC when they are reversed with 0.03 mg/kg neostigmine given at Ti of 25%.