The level of procalcitonin (PCT) in children is undetectable in healthy individuals
and slightly increased in Viral infections and noninfectious inflammatory
responses. It has been described to be notably increased in bacterial,
parasitic, or fungal infections.
Acute respiratory tract infections (ART!) of this study include, pharyngitis,
tonsillitis, rhinosinusitis, otitis media. As much as 75% of antibiotics are
prescribed for ART!, despite the mainly vityll origin.
The objective of this trail is to evaluate, if a PCT-guided diagnostic strategy
leads to reduction of antibiotic use for patients with ARTI in primary
care compared to standard approaches as C-reactive protein (CRP) and total
lettcocytic count (TLC).
This study included 110 children, 20 of them were apparently healthy as a
control group. The diseased group: 30 children with phatyngotonsillitis, 30
children had acute rhinosinusitis and 30 children with acute otitis media.
PCT, CRP and TLC were evaluated for control and diseased groups.
Culture for diseased group front blood, post nasal and ear discharge was |
