This study was carried out to assess the changes in serum creatine
phospholcinase (C.P.K), aspartate aminotransferase (A.S.T.), and alanine
aminotransferase (ALT.) levels in individuals with widely different levels
of physical fitness. We also tried to find a relation between these enzymes
and selected cardiorespiratory fitness parameters. Blood samples
were obtained from 16 professional players and 12 healthy but untrained
subjects (U.S.) at rest, five and 60 minutes after an ergometer test during
which cardiorespiratory data were obtained.
Ow- results showed that players demonstrated higher resting CPK
(P <0.001) and A.S.T. (p <0.05) levels than the US. C.P.K. and A.S.T.
reached their highest levels 5 minutes after the end of the ergomter test in
both groups, whilst peak A.L.T. was reached five and 60 minutes posttest
in the US. and players respectively . As regards C.P.K., as a marker
for muscle damage. players showed higher clearance rate from the blood
and lower magnitude of increases than U.S. Although fitness parameters
and serum enzyme levels demonstrated few significant correlation coefficients,
the change in serum C.P.K. showed most of the correlations with
the cardiorespiratory parametes. These results support the suggested hypothesis
that exercise temporarily increases the activities of serum A.S.T.,
C.P.K and to lesser extent of A.L.T. Physicians should be aware of these
elevations in muscle enzymes post exertion and interpret each in conjunction
with the athlete's symptoms.
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