The surgical treatment of nasal polyps (in bronchial hyperreactive patients)
is still controversial today because of the contradictory. in cons isten,
and unforeseen results reported in the literature.
44 patients with nasal polyposis, with no prior history of polypectomy,
were included in this study. Patients were studied with ventilatory
function tests and methacholine inhalation challenge (the provoking concentration.
PD20, was assessed) before and 3 months after undergoing
nasal polypectomy to determine the prevalence of bronchial hyperreactivity
(BHR). and to assess the effect of polypectomy on bronchial reactivity.
Patients with nasal polypi without asthma (23).8 (34.8%) had no evidence
of B.H.R.(PD20 > 4130 pgm) while the other 15 patients (65.296) had bronchial
hyperreactivity not reaching the range of asthma (P1)20 < 4130 but
not reaching ( 600 pgrn). After polypectomy of 15 non - asthmatic. hyperreactive
patients the mean increase in FVC, FEVI and P1)20 were statistically
significant. In 8 non - asthmatic non hypereactive patients the mean
increase in FVC, FEV1. FVC / FEV1 96 were non significant and the mean
PI320 was unchanged. In 21 asthmatic patients (PD20 (600 (gm) the
mean increase in PVC. FEVI, FVC / FEV1% and P1)20 were non significant
.
Our study indicates that (1) bronchial hyperreactivity is common in nasal
polyposis , (2) nasal polypectomy signcantly decrease bronchial hyperreactivity
in asymptomatic bronchial hyperreactive patients but not for
the asthmatic one. Improvement of the asthmatic condition may be partly
dependent upon a global toeatment of the patients |
