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Dr. Mohamed Salah Omar :: Publications:

Title:
METHOD OF PRODUCTION OF POLYANIONIC DRUG CARRIER CONJUGATES
Authors: BORATYNSKI JANUSZ MEGAHED MOHAMED SALAH OMAR KANSKA URSZULA NEVOZHAY DMITRY WIETRZYK JOANNA
Year: 2014
Keywords: Not Available
Journal: United States Patent
Volume: US 8,623,998 B2
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: International
Paper Link: Not Available
Full paper Mohamed Salah Omar _patentUSA 2014.pdf
Supplementary materials Not Available
Abstract:

The invention concerns the method of production of a polya nionic macromolecule which is a protein built, among others, from polar amino acids such as lysine, arginine, aspartic acid, glutamic acid), characteristic in that, as a result of the reaction between amine groups and the cyclic anhydride of dicarboxy lic acid, the charge changes towards more negatively charged carrier. This reaction gives rise to better therapeutic properties of macromolecules modi?ed in this way.

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