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Prof. Mohamed Salah Omar :: Publications: |
Title: | METHOD OF PRODUCTION OF POLYANIONIC DRUG CARRIER CONJUGATES |
Authors: | BORATYNSKI JANUSZ MEGAHED MOHAMED SALAH OMAR KANSKA URSZULA NEVOZHAY DMITRY WIETRZYK JOANNA |
Year: | 2014 |
Keywords: | Not Available |
Journal: | United States Patent |
Volume: | US 8,623,998 B2 |
Issue: | Not Available |
Pages: | Not Available |
Publisher: | Not Available |
Local/International: | International |
Paper Link: | Not Available |
Full paper | Mohamed Salah Omar _patentUSA 2014.pdf |
Supplementary materials | Not Available |
Abstract: |
The invention concerns the method of production of a polya nionic macromolecule which is a protein built, among others, from polar amino acids such as lysine, arginine, aspartic acid, glutamic acid), characteristic in that, as a result of the reaction between amine groups and the cyclic anhydride of dicarboxy lic acid, the charge changes towards more negatively charged carrier. This reaction gives rise to better therapeutic properties of macromolecules modi?ed in this way. |