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Dr. Ebtehal Maher Abdel Aal El-sayed :: Publications:

Title:
Significance of Expression of IMP3, PPARG & PD-L1 in Urothelial Carcinoma (Immunohistochemical Study)
Authors: Rasha M. El Sawi a, Ebtehal Abdel Aal a , Amr El-Sebaaie b , Nehal Zafer a, Hala Agina a
Year: 2020
Keywords: Urothelial carcinoma, IMP3, PPARG, PD-L1.
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: Local
Paper Link: Not Available
Full paper Ebtehal Maher Abdel Aal El-sayed_11.review .doc
Supplementary materials Not Available
Abstract:

Background: IMP3, PPARG and PD-L1 have been implicated in tumorigenesis and progression in many cancers, but their significance in urothelial carcinoma remains unclear. Aim: The aim of this study is to assess the possible significance of IMP3, PPARG and PD-L1 in urothelial bladder carcinoma and determine the relation between their expressions and different clinicopathological (tumor size, grade, histological variant, muscle invasion, lymphovascular invasion and pathologic T stage) and molecular variables. Methods: This study aimed to evaluate immunohistochemical expression of IMP3, PPARG and PD-L1 and correlate them with clinicopathological and molecular variables. Results: IMP3 was significantly correlated to muscle invasion (P

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