Background
Obesity and metabolic syndrome (MS) are global health concerns, with high rates of
cardiovascular morbidity and mortality. The current guidelines recommend lifestyle
modifications as the best initial treatment for obesity and MS. However, lifestyle
interventions have modest effects and high 1-year failure rates. Bariatric surgery
offers more weight loss with sustained effect in the long term.
Aim
The aim was to assess the effect of bariatric surgery on MS and all its components
and to detect the probable risk factors for persistent MS after bariatric surgery in
Egyptian patients.
Patients and methods
This prospective multicenter study included 250 obese patients who underwent
bariatric surgery and completed 1 year of postoperative follow-up. The patients
were evaluated preoperatively and at 1, 6, and 12 months postoperatively for
presence of MS and its components according to criteria of the third report of
National Cholesterol Education Program-Adult Treatment Panel (NCEP-ATP III).
Results and discussion
After 1 year of follow-up, the percentages of patients who had MS, obesity, type 2
diabetes mellitus, hypertension, hypertriglyceridemia, and low high-density
lipoprotein-cholesterol were significantly decreased from 92, 100, 84, 50, 74,
and 50% to 17, 2, 8, 17, 42, and 25%, respectively. Smoking, family history of
obesity, and less percentage of excess weight loss were the most important risk
factors for persistence of MS after bariatric surgery. |
