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Dr. Enas Mohamed Moustafa Sweed :: Publications:

Title:
167 Dynamic Contrast-Enhanced and Diffusion Weighted Magnetic Resonance Imaging: Useful Tools for Characterization of Ovarian Masses
Authors: Marwa A. Al Moafy a, Moharram A. Abdel Hai b, Enas M. Sweed a
Year: 2023
Keywords: Not Available
Journal: Not Available
Volume: Not Available
Issue: Not Available
Pages: Not Available
Publisher: Not Available
Local/International: Local
Paper Link: Not Available
Full paper Enas Mohamed Moustafa Sweed_4-Dynamic OV.pdf
Supplementary materials Not Available
Abstract:

Background: Determining whether a clinically diagnosed adnexal mass is benign or malignant is frequently not possible until surgical exploration and histologic examination are performed. This study aimed at evaluating the role of diffusion-weighted MRI and dynamic contrast enhanced MR in characterization of ovarian masses. Methods: This prospective study included 40 patients, conducted in Radiology department in Benha University hospital .During the period from December 2020 to March 2022. The study protocol was approved by the Local Ethical Committee. Results: the addition of the DWI improved the sensitivity, PPV, NPV and accuracy of the conventional MRI from 74%, 76%, 44% and 66% to 89%, 78%, 64% and 75% respectively, yet the specificity was decreased from 47 % to 41 %. We had 12 borderline ovarian tumours which showed variable appearance on DWI. About ten cases showed facilitated diffusion of its solid component with a high ADC value (1.4 x10-3mm2/S) suggesting benign pathology (false negative). Two cases showed restricted diffusion with high signal on DWIs and mean ADC value of 0.8 x10-3mm2/S, 7 lesions out of 17 (41.2%) showed steady rise with no definite peak (type 1 curve), and the other ten lesions (58.8 %) showed rapid rise with a plateau. Moreover, some of the invasive malignant lesions 18 (66.6 %) showed initial rapid steep early enhancement. Conclusion: DCE and DWIs sequences are good supportive techniques to conventional MRI in the categorization of ovarian masses into benign, borderline and invasive malignant tumours

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