To study the metabolic complication of using total parenteral nutrition (TPN), a healthy group of rats were employed. The TPN administrations had been associated with a recognizable loss of body weight gain (BWG) compared to normal nutrition. Losing of BW reached 8.3% in 5 days using diuretic drug (TPND). This was 6.2, 7.4 and 2.9 for TPN+ Parsley + Green tea (TPNPT), TPN+ Parsley (TPNP) and TPN alone, respectively.
Regarding urine secretion, there was no quite difference between the control and TPN solution, but, an almost double amount was secreted with both TPNP and TPND. The urine volume has been slightly reduced back when green tea was added to the parsley.
Hyperglycemia is a common metabolic complication associated with TPN, but, TPNPT seems to be relatively stronger in controlling blood sugar assuming it promotes an internal metabolic hypoglycemic role that facilitates utilization of sugar. Surprisingly, blood cholesterol has strongly been affected by TPN administration, wherein, tea with parsley is an excellent dietary therapy, meanwhile, the artificial drug used has a great reverse effect. The Fe in serum has been chosen to measure TPN action on blood conservative power. A great iron sweeping off was noticed especially when drug was added to the TPN. A noticeable reverse action has been accomplished when TPNPT was applied. Although a better result was recorded for TPNP, TPNPT was the best over all including the control. In some other words, TPN+ Parsley+ Green tea obviously of great Fe retention potency, meanwhile, the greatest loss of Fe is caused by TPND followed by some significant level of TPN alone. In conclusion, an internal metabolic homeostatic power is seen for TPNPT combination in area of nutritional biochemistry and dietary therapy.