Summary
Left ventricular remodeling is disadvantageous process resulting in progressive enlargement with systolic dysfunction and associated with worse outcomes .
Despite studies evaluating various clinical factors and routine echocardiographic parameters predisposing to left ventricular remodeling as a consequence of myocardial infarction, there are still gaps and some of these parameters failed to identify patients prone to left ventricular remodeling. Tissue Doppler imaging derived strain analysis also has limited value in prediction of left ventricle structural changes .
Speckle tracking echocardiography (STE) is relatively new echocardiographic method for evaluating both global and regional strain .
So, this study aimed at determining value of global longitudinal strain in the prediction of left ventricular remodeling in patients after primary coronary angioplasty in acute anterior myocardial infarction.
100 patients with anterior STEMI were enrolled in this study, their age ranged from 53-65years old. They were divided into 2 groups &assessed for patient demographics, history, clinical presentation, investigations, in-hospital management .
♦ Group I: included 74 patients without left ventricular remodeling .
♦ Group II: included 26 patients with left ventricular remodeling .
The sex ratio &risk factors including hypertension, diabetes& smoking
were similar in both groups.
There were no significant difference in clinical finding at presentation and number of coronary artery affected between 2 groups .
No difference were found between patients with & without LV remodeling as regard LV volumes , LVEF%, WMSI and LV diastolic function.
At the univariable analysis; use of betablocker (BB), global longitudinal (GLS) and circumferential strain (GCS) were significantly associated with LV remodeling (P value |