Summary
Cardiovascular diseases are common in patients with end stage renal disease (ESRD) and are the main causes of morbidity and mortality. A large body of evidence has accrued indicating that a portion of this cardiovascular damage may be due to haemodialysis. (Ritz E, et al ., 2009)
Haemodialysis provides a unique opportunity to evaluate the effect of a preload reduction on Doppler parameters currently used to assess LV diastolic properties. In this specific setting, recent clinical studies conducted in patients with chronic renal failure have yielded discrepant results (Fijalkowski M, et al., 2006)
The aim of the study was to assess acute changes in tissue Doppler parameters for patients with end stage renal disease on regular hemodyalsis.
This study had been conducted in Cardiology Department, Faculty of Medicine, Benha University) from January 2017 to April 2018. The study population has been randomly selected from the cardiology department and haemodialysis unit. The patients diagnosed with ESRD on regular haemodialysis were included in the study.
The most important finding in our study results was that there was single HD therapy was related to acute deterioration in diastolic parameters as examined by conventional Doppler echocardiography.
Both mitral inflow E and A velocities declined after HD treatment. Because E velocity decreased more than A velocity, the E/A ratio diminished as well.
Regarding the parameters of diastolic dysfunction studied, we did not find a significant difference in the pre- and post-hemodialysis ratio between the early diastolic mitral annulus velocity (Em) and the late atrial mitral annulus velocity (Am), measured by tissue Doppler and averaged for the septal, lateral, anterior and posterior annulus. Moreover, observing the pulsed Doppler pulmonary vein flow, the velocity of the systolic (S) wave and the ratio between the systolic and diastolic (D) waves did not change significantly after hemodialysis, although some variability was observed in the velocity of the D wave ,This finding differs from the results of our study .
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