Background: global longitudinal strain (GLS) has clinical and
prognostic significance in heart failure with preserved ejection
fraction (HFpEF). Aim: evaluate left ventricular strain in
patients with HFpEF and its relation with adverse events
(hospitalization and mortality). Methods: 100 patients were
admitted, as per inclusion criteria: Heart failure with preserved
ejection fraction, while those with hemodynamic instability,
cardiogenic shock, inadequate echogenic window, or lower
ejection fraction were excluded. Every patient was evaluated
using baseline transthoracic echocardiography, speckle tracking
echocardiography, routine laboratory tests, history taking,
demographic data gathering, and a thorough clinical examination.
Results: The mean ± SD of the left-ventricular ejection fraction
was 60.17 ± 5.29 percent, with a range of 50 to 70%. The mean
± SD of the left ventricular mass index was 79.8 ± 12.41 g/m2,
with a range of 50 to 110 g/m2. With respective ranges of 25.7–
40.2 mm and 38.9–57.2 mm, the mean ± SD values for the left
ventricular end-systolic and diastolic diameters were 31.8 ± 2.86
mm and 47.91 ± 3.44 mm. The mean ± SD of the global
longitudinal strain was -18.89 ± 3.11 percent, with a range of -13
to -23%. The mean ± SD of the global circumferential strain was
-19.89 ± 3.11 percent, with a range of -14 to -24 percent. 3
months periodic follow up including assessment of clinical
variables, mortality and re-hospitalization. Conclusion,
compared to event-free heart failure with maintained ejection,
individuals with an event showed much reduced global
longitudinal strain and global circumferential strain. |
