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Dr. Mohamed Ali El Awadi Ali Khater :: Theses : |
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| Title | Prognostic Value of Speckle Tracking & 3D ECHO Cardiography in Patients with Acute ST Segment Elevation Myocardial Infarction |
| Type | MSc |
| Supervisors | Khaled E. El Rabbat (MD), Al-Shaimaa M. Sabry(MD), Shereen M. Farag (MD) |
| Year | 2019 |
| Abstract | The prognosis of the patients bearing acute myocardial infarction (AMI) with ST‑segment elevation is related to the cardiac mechanics and to the geometry of the left ventricle (LV) as well. The percentage of dilatation of the LV (ventricular remodeling) and the myocardial performance mirrored by the variation of the ventricular volumes (ejection fraction) are aspects of great prognostic importance in the clinical evolution of the patients after AMI. LV remodeling is an important factor in the pathophysiology of advancing heart failure (HF) and several studies support the role of measures of LV remodeling in the clinical investigation of novel HF treatments. Postinfarct ventricular remodelling develops in about 30% patients with a history of myocardial infarction. As remodelling depends on infarct size, it is likely that its prevalence is higher in the subgroup of patients without any or successful reperfusion. Emerging echocardiographic techniques, STE; strain & strain-rate imaging has gained acceptance for its usefulness in defining the degree of myocardial deformation and contractility in patients with various cardiac diseases. It also might be more accurately reflecting intrinsic measures of myocardial contractility and enable quantification of regional myocardial deformation which allowed for analysis of longitudinal and circumferential motion and have contributed substantially to the understanding of cardiac mechanics. The featuring parameters of 2D speckle tracking analysis include global longitudinal strain (GLS), global circumferential strain (GCS) and torsion. Those parameters independently reflect complex cardiac 3D contraction. Many studies have agreed on the fact that GLS and GCS correspond to sub-endocardial and mid-wall functions, respectively. These parameters are associated with cardiac viability and adverse outcome. The 3D echocardiogram allows for the structural analysis of the heart from multiple spatial planes of observation. The 3D echocardiographic analysis of the LV, when compared to the 2D analysis, presents a finer proximity with the measurements obtained with methods of a better spatial resolution, such as the 64‑channel ultra-rapid computed tomography and the nuclear magnetic resonance. |
| Keywords | prognosis;speckle;tracking;ECHO;3D;STEMI;infarction; |
| University | Benha University |
| Country | Egypt |
| Full Paper | download paper |
| Title | Assessment of left atrial and left ventricular functions in hypertensive patients with sinus rhythm and atrial fibrillation using tissue Doppler imaging |
| Type | PhD |
| Supervisors | S.I.Farag, S.A.Mustafa and H.S.Kabil |
| Year | 2022 |
| Abstract | Hypertension (HTN) is the leading preventable risk factor for cardiovascular disease (CVD) and all-cause mortality worldwide. Despite the implementation of new clinical guidelines and the broad availability of effective pharmaceutical agents, HTN often goes undetected and inadequately treated, shortening life expectancy by five years during adulthood. Long term HTN leads to hypertensive heart disease and is the result of anatomical and functional changes in the cardiovascular system (which is a cardiovascular sequela of HTN) and is defined as left ventricular hypertrophy (LVH), left atrial enlargement, left ventricular diastolic dysfunction, functional mitral regurgitation, and neuro-hormonal changes. Tissue tracking and strain rate imaging are new echocardiography modalities on the basis of Doppler tissue imaging, and they may be used to assess the regional systolic shortening of the LV. Strain rate analysis evaluates whether the regional myocardium is stretching or shortening. |
| Keywords | Hypertension, Echocardiography, AF, Strain, Tissue Doppler imaging. |
| University | Benha University |
| Country | Egypt |
| Full Paper | download paper |
