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Assist. Tasneem Yasser Afifi Elsayed Kilany :: Theses :

Title Variation of regional distribution of enteroendocrine cells in small and large intestine of camel: histological and immunohistochemical study
Type PhD
Supervisors Tasnim Y. El keliny, Ehab M. El Zoghby, Hossam F. Attia, Mona N. Hussien
Year 2025
Abstract The enteroendocrine cells (EECs) are gut-associated endocrine cells. They secrete various kinds of locally and systemically acting amines and peptides. In this study, the EECs' distribution, shape, and staining properties were demonstrated in the intestine of the camel (Camelus dromedarius). hematoxylin and eosin, iron hematoxylin, Churukian and Schenk, and chromogranin A immunohistochemistry were used to identify EECs in various intestinal segments. Our results indicated that EECs have three different shapes: spindle, cone, and round. They were primarily located in the crypts of Lieberkühn. The number of positive immunostained EECs was higher in the small intestine than in the large intestine (P = 0.0030). The duodenum had the highest portion of EEC count in the small intestine, followed by the jejunum and the ileum. The colon had the highest portion in EECs count in the large intestine, followed by the rectum and then the caecum (P = 0.0030). In conclusion, our findings indicated the presence of three different kinds of EECs in the small and large intestines of camels.
Keywords Intestine Enteroendocrine cells camel immunohistochemistry
University benha
Country egypt
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