Introduction: Recurrent tonsillitis is a common pediatric condition characterized by frequent episodes of pharyngeal inflammation, often associated with Streptococcus pyogenes (Group A Streptococcus) infections. The aim of this work was to evaluate the role of 0.5% Povidone-Iodine and H2 O2 mouth rinse/gargle on streptococcus pyogenes biofilmproducing bacteria in recurrent tonsillitis in children between 4-18 years. Methods: This interventional study was carried out on 90 patients aged from 6 to 18 years old, both sexes, with recurrent exacerbations of chronic tonsillitis. Patients were divided in to three equal groups: Group (A): Chronic tonsilitis patients scheduled for tonsillectomy, received 0.5% povidone-iodine mouth rinse/gargle. Group (B): Chronic tonsilitis patients scheduled for tonsillectomy, received H2 O2 solution. Group (C): Chronic tonsilitis patients scheduled for tonsillectomy as control group. Results: There were no significant differences in the distribution of Grade III and Grade IV hypertrophy among the groups. However, bacterial analysis revealed a significant difference in the prevalence of Streptococcus pyogenes, Staphylococcus aureus, and Streptococcus agalactiae, with Streptococcus pyogenes being most frequently isolated, particularly in the H2 O2 group. Spectrophotometric assessment demonstrated a highly significant difference in biofilm mass, with the untreated control group exhibiting much higher optical density values compared to the treated groups. Conclusion: Povidone iodine and hydrogen peroxide mouth rinses may effectively diminish biofilm formation and bacterial colonization in the management of recurrent tonsillitis, particularly against Streptococcus pyogenes, and it is recommended to integrate antiseptic mouth rinses into treatment protocols and postoperative care. |
