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Dr. Abdelmoneim Ahmed Abdelmoneim Elsayed :: Publications: |
Title: | ENDOTHELIAL NITRIC OXIDE SYNTHASE 4A/B POLYMORPHISM AND ITS INTERACTION WITH
G894T VARIANTS IN TYPE 2 DIABETES MELLITUS : PREDICTING THE RISK OF DIABETIC
NEPHROPATHY |
Authors: | Azza Abo Senna, 1Jehan H Sabry, 1Mohamed A Al Hindi, 1Hesham A Eissa, 2Abdelmonem Ahmed, and Basma M Salem. |
Year: | 2016 |
Keywords: | eNOS polymorphism, Type 2 DM, Diabetic nephropathy. |
Journal: | Not Available |
Volume: | Not Available |
Issue: | Not Available |
Pages: | Not Available |
Publisher: | Not Available |
Local/International: | International |
Paper Link: | Not Available |
Full paper | Abdelmoneim Ahmed Abdelmoneim Elsayed_19120_3 (3).pdf |
Supplementary materials | Not Available |
Abstract: |
Background: nitric oxide synthase (eNOS) and it regulates endothelial function. The presence of might further complicate endothelial dysfunction and nephropathy through reduced production of NO. This study polymorphisms on the risk of diabetic nephr Patients and Methods: healthy subjects serving as a control group. All candidates were genotyped polymorphism using PCR Results control for eNOS G894T and (4a/b) Polymorphisms differences with p value and macroalbuminuria when compared with controls but the presence of effect. Conclusion: 4a or 894T allele, the risk of developing DN increased significantly. However, the presence of both alleles together was |